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Submitted: 12 Jul 2020
Revision: 12 Aug 2020
Accepted: 15 Aug 2020
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  Abstract View: 26

Original Article

Evaluation of salivary calcium, phosphorus and alkaline phosphatase concentration before and after the first phase of the periodontal treatment in patients with chronic periodontitis

Jaber Yaghini ORCID logo, Samaneh Khashei, Zohreh Afshari ORCID logo, Ahmad Mogharehabed* ORCID logo

Abstract

Abstract Introduction: Evaluation of salivary biomarkers is a non-invasive, convenient and economical method for diagnosis of many diseases. Evidence shows that salivary biomarkers and periodontal disease may be correlated. This study was conducted to evaluate the effect of phase I periodontal therapy on salivary concentration of calcium, phosphorous and alkaline phosphatase (ALP). Methods and material: In this descriptive, analytical study, 16 patients were selected among those referred to the Department of Oral Medicine at Isfahan University of Medical Sciences, using convenience sampling. Saliva samples were collected using the drooling method. The salivary concentrations of calcium, phosphorous and ALP were measured immediately after saliva collection, before the first phase of periodontal therapy and 1 month later, using colorimetric assay. The collected data were analyzed using SPSS software via paired T-test. P<0.05 was considered statistically significant. Results: The salivary concentrations of calcium, phosphorous and ALP were 6.68 mg/dL, 20.57 mg/dL, and 48.31 mg/dL, respectively before and 7.15 mg/dL, 22.51 mg/dL, and 40.37 mg/dL, respectively after phase I periodontal therapy. There was no significant difference between the salivary levels of calcium, phosphorous and ALP before and after phase I periodontal therapy (P>0.05). Conclusion: The results of this study revealed that the salivary concentration of calcium, phosphorous and ALP remained relatively unchanged after phase I periodontal therapy.
Keywords: : Periodontal disease, Saliva, Calcium, Phosphorus, Alkaline phosphatase
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