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Submitted: 07 Apr 2014
Accepted: 07 Jul 2014
ePublished: 08 Oct 2014
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J Periodontol Implant Dent. 2014;6(2): 60-63.
doi: 10.15171/jpid.2014.011
  Abstract View: 166
  PDF Download: 144

Case Report

Leukemia-induced Gingival Overgrowth as an Early Manifestation in Pregnancy: A Case Report

Parichehr Behfarnia 1, Parviz Deyhimi 2, Abbas Haghighat 1, Vahid Naemi 4, Narges Naghsh 5*

1 Assistant Professor, Department of Periodontology and Torabinejad Dental Research Center, School of Dentistry, Isfahan University of Medical Sciences, Isfahan, Iran
2 Associate Professor, Department of Oral and Maxillofacial Pathology and Torabinejad Dental Research Center, School of Dentistry, Isfahan University of Medical Sciences and, Isfahan, Iran
3 Assistant Professor, Department of Oral and Maxillofacial Surgery and Torabinejad Dental Research Center, School of Dentistry, Isfahan University of Medical Sciences, Isfahan, Iran
4 Postgraduate Student, Department of Oral and Maxillofacial Surgery and Torabinejad Dental Research Center, School of Dentistry, Isfahan University of Medical Sciences, Isfahan, Iran
5 Assistant Professor, Department of Periodontology and Torabinejad Dental Research Center, School of Dentistry, Isfahan University of Medical Sciences, Isfahan, Ira
*Corresponding Author; E-mail: n_naghsh@dnt.mui.ac.ir

Abstract

Leukemia is a neoplastic disease with early oral and periodontal manifestations such as ulceration, infection, bleeding and gingival hyperplasia. This paper describes a 39-year-old pregnant woman with a diagnosis of acute myelomonocytic leukemia (AML), with gingival enlargement in the upper and lower jaws. A gingival biopsy was performed, followed by a complete blood count and peripheral blood smear. From a histopathological view, infiltration of the neoplastic (myelomonocytoblastic) cells was observed and many immature lymphoid cells were revealed by the hematologic tests. The interesting clinical finding about this case was the absence of spontaneous bleeding and profuse bleeding on probing. This case is reported to emphasize the leukemia-induced gingival enlargement in pregnancy and the early diagnosis of AML by dentists, which results in immediate treatment and management of the patient.
Keywords: Gingival overgrowth, Leukemia, Oral manifestation
 
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