Nima Naddafpour
1 
, Hassan Semyari
2,3 , Hadise Semyari
3 , Rozhan Khaledtaj
1 , Hossein Semyari
1,3* 1 Department of Periodontics, TeMS.C., Islamic Azad University, Tehran, Iran
2 Department of Periodontics, Faculty of Dentistry, Shahed University, Tehran, Iran
3 Heuma Training Center, Tehran, Iran
Abstract
Florid cemento-osseous dysplasia (FCOD) is a benign fibro-osseous disorder characterized by altered and poorly vascularized bone, which complicates implant placement by increasing the risk of infection and impaired healing. This case report documents the successful placement and one-year follow-up of two dental implants in the posterior mandible of a 45-year-old female patient with FCOD. Radiographic and clinical evaluations confirmed stable osseointegration and successful functional restoration, with no complications or changes in lesion size during follow-up. These findings suggest that, with careful patient selection, the use of atraumatic surgical techniques, meticulous infection control, appropriate postoperative oral care, and consistent follow-up, dental implant therapy can be successfully performed in selected cases of FCOD. However, due to the limited reported cases, extensive longitudinal studies are required to guide implant therapy in patients with FCOD.