Tooth-Derived Graft for Preservation and Reconstruction of Orofacial Bones: A Comprehensive Review
Abstract
Bone loss in the craniofacial region can result from various causes, requiring grafting for restoration. Each type of bone graft has its own advantages and disadvantages. In recent years, an increasing number of clinical research studies have used extracted teeth as grafting biomaterials. The purpose of this study was to outline the utilization of teeth as bone graft material, describe a general protocol for tooth graft material production, compare various manufacturing methods, and assess tooth-derived grafts in comparison to other bone graft materials. The review was based on electronic database searches including Scopus, PubMed, Cochrane, Web of Science, and Google Scholar, using various combinations of keywords such as "autogenous graft," "autologous graft," "human dentin," "dentin matrix," "tooth graft," "demineralized dentin matrix," and related terms applied to titles, abstracts, and keywords. Tooth-derived grafts demonstrate promising outcomes comparable to conventional bone graft materials. However, further research is needed to standardize protocols and validate clinical applications.